Author
Anthony P. Acenas,
Princess Carlyle P. Bayawa,
Anjelle Mara C. Belleza,
Mark Lourence D. Cuyos,
Karen C. Del Rosario,
Kevin James V. Ferraren,
Cleo A. Gomez,
Christian Gerlie B. Gonzales,
Marlon V. Montolo,
Floriza L. Muñez,
Reina Katrina S. Regis,
Chelsea Lei R. Sartorio
Related Institution
School of Medicine - University of Cebu - Banilad Campus - University of Cebu
Publication Information
Publication Type
Thesis/Dissertations
Publication Date
June 2018
Abstract
Introduction: Antibiotics are agents that kill bacterial pathogens but with the rising antibacterial resistance due to misuse, overuse, and unable to comply with the complete regimen, it has become a major threat in the society. Thus, it is very important to monitor the present of antibiotic usage to prevent further resistance because if this happens, no other antibiotic would work as therapy. Through hospital antibiograms, it would help the health sector in empiric treatment and in the surveillance of trends of antibacterial resistance.
Methods: The data gathered from the WHONET (World Health Organization Network) Integrated System of the Microbiology laboratory from January to December 2017 was tabulated according to bacteria isolated (Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, and Pseudomonas aeruginosa), resistance rate (&R) of different antibiotics, and departments of University of Cebu Medical Center namely MED, ICU, PED, and CCU. This data was generated to make an antibiogram for the whole year of 2017. The average of the resistance rate (%R) of each antibiotic was calculated using Microsoft Excel. The number of isolates per organism and per department were also identified.
Results: It was identified that Ampicilin had the highest amount of resistance (%R) to the bacterial strains except for Pseudomonas aeruginosa, in which none of the antibiotics showed any resistance to. Amikacin, meanwhile, was observed to have the least amount of resistance in all the bacterial strains.
Conclusion: Ampicillin showed the highest mean resistance against the four bacterial strains. This means that this antibiotic treatment option is no longer effective in treating infections against these pathogens. On the other hand, Amikacin showed the least resistance, thus it is effective for treatment of the four gram negative organisms.
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