Jose Mari Barrios III,
Maxine O. Caindec,
Alyssa Dawn C. Ditucalan,
Alfil Romulo P. Estrera,
Sharmaine Josh O. Li,
Ralph Pearvin G. Mission,
Ian M. Puebla,
Caryl Ann A. Rabanos,
Mico D. Rosatase,
Keejina G. Samsuya
School of Medicine - University of Cebu - Banilad Campus - University of Cebu
INTRODUCTION: Methicillin-resistant staphylococcus aureus is a growing concern in the pharmaceutical endeavors. The study suggests taking advantage of bioinformatics to predict possible new drug actions on the MRSA.
METHODS: Theoretical approach using previously submitted genome sequence of plants and MRSA were collected and analyzed using both I-TASSER for homology characterization and HEX protein docking- protein interaction.
RESULTS: 3 plant proteins have shown stable protein- protein configuration with the MRSA trans membrane proteins as qualified by the various HEX docking parameters.
CONCLUSION: Bioinformatics can be used to determine potential drug actions in terms of protein-protein interactions.
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