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Potentially new drug action against Methicillin-Resistant Staphylococcus aureus (MRSA) via iterative threading assembly refinement and Hex Protein Docking.


Jose Mari Barrios III,
Maxine O. Caindec,
Alyssa Dawn C. Ditucalan,
Alfil Romulo P. Estrera,
Sharmaine Josh O. Li,
Ralph Pearvin G. Mission,
Ian M. Puebla,
Caryl Ann A. Rabanos,
Mico D. Rosatase,
Keejina G. Samsuya

Related Institution

School of Medicine - University of Cebu - Banilad Campus - University of Cebu

Publication Information

Publication Type
Thesis Degree
Publication Date
June 2018


INTRODUCTION: Methicillin-resistant staphylococcus aureus is a growing concern in the pharmaceutical endeavors. The study suggests taking advantage of bioinformatics to predict possible new drug actions on the MRSA.

METHODS: Theoretical approach using previously submitted genome sequence of plants and MRSA were collected and analyzed using both I-TASSER for homology characterization and HEX protein docking- protein interaction.

RESULTS: 3 plant proteins have shown stable protein- protein configuration with the MRSA trans membrane proteins as qualified by the various HEX docking parameters.

CONCLUSION: Bioinformatics can be used to determine potential drug actions in terms of protein-protein interactions.


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Physical Location

LocationLocation CodeAvailable FormatAvailability
University of Cebu - School of Medicine T/Ba27po/2018c.1 Abstract Print Format

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